Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PLD2 | O14939 | 4/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870356 | 1.00 | POLB (0.48) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL28503359 | 1.00 | POLB (0.48) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL22869425 | 0.93 | HSD11B1 (0.49) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL28500779 | 0.93 | HSD11B1 (0.49) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL30870157 | 0.93 | HSD11B1 (0.49) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL22869755 | 0.91 | HSD11B1 (0.56) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL30870121 | 0.91 | HSD11B1 (0.56) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL28509295 | 0.91 | HSD11B1 (0.56) | POLBHPGDHSD11B1PLD2PLD1 | |
| SCHEMBL22869396 | 0.88 | HTT (0.49) | HPGDHSD11B1PLD2PLD1CHRM1 | |
| SCHEMBL28499858 | 0.88 | HTT (0.49) | HPGDHSD11B1PLD2PLD1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002250-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002250-A1 | SUBSTITUTED BENZODIAZOLES AND USE THEREOF IN THERAPY | XDH, CYP4X1, CYP11B2 | POLB 3729/4885HPGD 1382/4885HSD11B1 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.