SCHEMBL22870967

SCHEMBL22870967

O=C(O)c1ccccc1-c1ccc2c3ccc(-c4ccccc4C(=O)O)cc3c3nc4c(-c5cccc6c5sc5ccccc56)sc(-c5cccc6c5sc5ccccc56)c4nc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PARP14 Q460N5 1/20 0.39
MCL1 Q07820 1/20 0.39
ACMSD Q8TDX5 1/20 0.39
ALDH1A1 P00352 1/20 0.38
PRKDC P78527 1/20 0.37
PRSS12 P56730 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
UCHL5 Q9Y5K5 1/20 0.36
SOS1 Q07889 1/20 0.36
PDE10A Q9Y233 1/20 0.35
DHODH Q02127 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22870943 0.88 SLC6A3 (0.46) ALOX5PARP14ALDH1A1MEN1KMT2A
SCHEMBL22871101 0.84 SOS1 (0.39) ALOX5MCL1ACMSDALDH1A1PRSS12
SCHEMBL22870741 0.81 ALOX5 (0.45) ALOX5PARP14ALDH1A1PRKDCNPC1
SCHEMBL22870703 0.80 ALOX5 (0.44) ALOX5ALDH1A1PRKDCMEN1KMT2A
SCHEMBL22870522 0.79 PTPRF (0.46) ALOX5MCL1ACMSDDHODH
SCHEMBL29325889 0.77 ALOX5 (0.42) ALOX5PARP14ALDH1A1PRKDCRAB9A
SCHEMBL21185975 0.77 ALOX5 (0.54) ALOX5PARP14PRKDC
SCHEMBL11955471 0.74 ALOX5 (0.51) ALOX5PARP14PRKDCDHODH
SCHEMBL22870719 0.74 TNKS (0.41) ALOX5PARP14ALDH1A1PRKDCNPC1
SCHEMBL21185887 0.74 ALOX5 (0.48) ALOX5PARP14PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 US disclosed
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 US disclosed
US-20210002294-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002294-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME CRY1, FLI1, FDFT1 ALOX5 1011/4885PARP14 2484/4885MCL1 253/4885
US-12043627-B2 Compound and color conversion film comprising same CRY1, FLI1, FDFT1 ALOX5 1011/4885PARP14 2484/4885MCL1 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.