Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301891 | 0.80 | LMNA (0.43) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL9802941 | 0.78 | LMNA (0.42) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL10798128 | 0.74 | LMNA (0.39) | LMNAGABRA1GABRB1HTT | |
| SCHEMBL929797 | 0.74 | — | — | |
| SCHEMBL27585244 | 0.72 | LMNA (0.37) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL930869 | 0.72 | — | — | |
| SCHEMBL1819414 | 0.71 | GAA (0.46) | LMNAHPGDTSHRMAPTKMT2A | |
| SCHEMBL67859 | 0.70 | LMNA (0.58) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL501283 | 0.70 | LMNA (0.39) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL1492630 | 0.68 | ALDH1A1 (0.34) | LMNACYP3A4HPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465882-A4 | HETROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1465882-A2 | HETROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X-Ceptor Therapeutics, Inc. (US) | 2004-10-13 | — | — | EP | claimed |
| US-6696473-B2 | THIAZOLIDINONE DERIVATIVES; MODULATING CHOLESTEROL METABOLISM | X-CEPTOR THERAPEUTICS, INC. | 2004-02-24 | — | — | US | claimed |
| WO-2003060078-A9 | HETEROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2004-02-19 | — | — | WO | claimed |
| US-20030212111-A1 | Heterocyclic modulators of nuclear receptors | AKARNA THERAPEUTICS, LTD. (GB) | 2003-11-13 | — | — | US | claimed |
| WO-2003060078-A2 | HETEROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| US-8003297-B2 | Polymeric material, containing a latent acid | BASF SE (DE) | 2011-08-23 | — | — | US | disclosed |
| US-20100093950-A1 | POLYMERIC MATERIAL, CONTAINING A LATENT ACID | CIBA CORPORATION | 2010-04-15 | — | — | US | disclosed |
| US-7655380-B2 | Polymeric material, containing a latent acid | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090155716-A1 | Polymeric material containing a latent acid, i.e. a compound which is not an acid but which can be converted to an acid by the influence of laser irradiation | HENEGHAN MICHAEL | 2009-06-18 | — | — | US | disclosed |
| EP-1407322-B1 | LASER MARKING METHOD | CIBA HOLDING INC (CH) | 2008-12-17 | — | — | EP | disclosed |
| US-7264916-B2 | Laser marking method | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070054220-A1 | Polymeric material, containing a latent acid | HENEGHAN MICHAEL | 2007-03-08 | — | — | US | disclosed |
| US-4734519-A | STABILIZERS | MALLINCKRODT, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0250087-A1 | Pentaerythritol co-esters | MALLINCKRODT, INC. (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4539354-A | PHOSPHITE DERIVATIVE OF A PHENOL, A GROUP II METAL CARBOXYLATE ANDAN ESTER OF A POLYOL | ALLIED CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0032586-B1 | DURABLE POLYESTER MOLDING COMPOSITION | GAF CORPORATION (US) | 1984-01-11 | — | — | EP | disclosed |
| EP-0069195-A2 | Stabilized ethylene/chlorotrifluoroethylene copolymer composition | Ausimont, U.S.A., Inc. (US) | 1983-01-12 | — | — | EP | disclosed |
| EP-0032586-A2 | Durable polyester molding composition | GAF CORPORATION (US) | 1981-07-29 | — | — | EP | disclosed |
| US-4277391-A | CONTAINING THREE DIFFERENT TYPES OF ANTIOXIDANTS | GAF CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212111-A1 | Heterocyclic modulators of nuclear receptors | NR1H2, NR1H3, NR1H4 | LMNA 2921/4885TRPA1 797/4885SLC6A2 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.