Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301891 | 0.80 | LMNA (0.43) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL5092552 | 0.79 | CA1 (0.32) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL2287151 | 0.78 | LMNA (0.47) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL8025080 | 0.78 | TRPA1 (0.42) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL28120150 | 0.74 | TRPA1 (0.38) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL27585244 | 0.72 | LMNA (0.37) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL6118119 | 0.71 | SLC9A1 (0.31) | — | |
| SCHEMBL67859 | 0.70 | LMNA (0.58) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL71456 | 0.68 | LMNA (0.56) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL19439651 | 0.67 | GABRA1 (0.42) | LMNASLC6A2HTR2BTRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051460-A | Chlorotrifluoroethylene-ethylene copolymer with heat resistant stabilizers, epoxy resins, phosphites and esters | AUSIMONT, U.S.A., INC. (US) | 1991-09-24 | — | — | US | disclosed |