Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | LCK | P06239 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 5/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22871913 | 0.91 | KDM4E (0.71) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL246218 | 0.86 | KDM4E (1.00) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL29397959 | 0.86 | KDM4E (1.00) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL12221062 | 0.86 | KDM4E (0.80) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL4929657 | 0.85 | KDM4E (0.78) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL30050571 | 0.83 | KDM4E (0.70) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL22871876 | 0.83 | KDM4E (0.74) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL20844616 | 0.83 | KDM4E (0.67) | KDM4ELCKALDH1A1HPGDCYP2D6 | |
| SCHEMBL13839157 | 0.82 | AKR1B1 (0.72) | KDM4ELCKALDH1A1HPGDCA12 | |
| SCHEMBL67779 | 0.82 | CYP2D6 (0.72) | KDM4ELCKALDH1A1HPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220308043-A1 | FLUORESCENT PROBES FOR IDENTIFICATION AND QUANTIFICATION OF HEPATIC TRANSPORTERS IN VITRO AND IN VIVO | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-09-29 | — | — | US | disclosed |
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ST6GAL1, NEU1, GALNT1 | KDM4E 4044/4885LCK 1019/4885ALDH1A1 1642/4885 |
| US-20220308043-A1 | FLUORESCENT PROBES FOR IDENTIFICATION AND QUANTIFICATION OF HEPATIC TRANSPORTERS IN VITRO AND IN VIVO | ABCB11, SLC10A1, SLC10A2 | KDM4E 4836/4885LCK 4735/4885ALDH1A1 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.