Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287336 | 0.89 | MAPT (0.49) | KCNH3SMN1; SMN2ALDH1A1NPC1POLB | |
| SCHEMBL2285408 | 0.89 | LMNA (0.53) | KCNH3SMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL2283651 | 0.87 | PAK4 (0.55) | SMN1; SMN2ALDH1A1KDM4EHTTMAPK1 | |
| SCHEMBL2278895 | 0.86 | CCNT1 (0.46) | KCNH3SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL2284523 | 0.85 | AURKA (0.50) | MAPTLCKKDRCDK2CDK4 | |
| SCHEMBL2283329 | 0.84 | KCNH3 (0.42) | KCNH3KDM4ETNK2MAPK1ALOX15 | |
| SCHEMBL27741378 | 0.83 | CDK4 (0.55) | KCNH3SMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL2281705 | 0.82 | KCNH3 (0.54) | KCNH3SMN1; SMN2ALDH1A1NPC1KDM4E | |
| SCHEMBL2283774 | 0.82 | IKBKB (0.41) | KCNH3SMN1; SMN2ALDH1A1NPC1HTT | |
| SCHEMBL2284122 | 0.81 | KCNH3 (0.50) | KCNH3SMN1; SMN2ALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | KCNH3 1030/4885SMN1; SMN2 4306/4885ALDH1A1 707/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | KCNH3 1123/4885SMN1; SMN2 4384/4885ALDH1A1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.