Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19188274 | 0.77 | BTK (0.41) | HSD11B1EPHX1KMT2ADGAT1BTK | |
| SCHEMBL22874207 | 0.69 | CACNA1H (0.38) | EPHX1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL2002673 | 0.68 | EPHX1 (0.55) | EPHX1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL12942650 | 0.68 | EPHX1 (0.67) | EPHX1ALDH1A1KMT2ABTKGAA | |
| SCHEMBL23562416 | 0.68 | HSD11B1 (0.49) | HSD11B1MEN1KMT2ABTKGAA | |
| SCHEMBL24337073 | 0.68 | HSD11B1 (0.49) | HSD11B1MEN1KMT2ABTKGAA | |
| SCHEMBL23329861 | 0.67 | CYP4F2 (0.33) | — | |
| SCHEMBL20832773 | 0.66 | CA1 (0.38) | HSD11B1MEN1KMT2ABTKGAA | |
| SCHEMBL20113152 | 0.66 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL19189061 | 0.65 | SLC6A12 (0.34) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004516-A1 | METHOD FOR PREPARING 2-INDOLINOSPIRONE COMPOUND AND INTERMEDIATE THEREOF | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2021-01-14 | — | — | WO | disclosed |