Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503938 | 0.85 | CCR3 (0.54) | KDM4EAPOBEC3AAPOBEC3GKMT2AMEN1 | |
| SCHEMBL22875382 | 0.80 | L3MBTL1 (0.66) | KDM4EHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL18711458 | 0.79 | L3MBTL1 (0.51) | CNR1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL22874751 | 0.78 | SMN1; SMN2 (0.58) | KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22874685 | 0.76 | GPR119 (0.53) | GPR119KDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL13503788 | 0.76 | KDM4E (0.61) | KDM4EKMT2AMEN1EPHX2L3MBTL1 | |
| SCHEMBL22875386 | 0.76 | MAPT (0.50) | KDM4EAPOBEC3AAPOBEC3GHPGDKMT2A | |
| SCHEMBL8665194 | 0.76 | L3MBTL1 (0.48) | CNR1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL18701998 | 0.75 | L3MBTL1 (0.48) | CNR1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL2603243 | 0.75 | KDM4E (0.50) | CNR1KDM4ESMN1; SMN2EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | C4 THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | C4 THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-20210009559-A1 | CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS | C4 THERAPEUTICS, INC. (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | CRBN, IKZF1, IKZF3 | GPR119 3820/4885CNR1 4469/4885C3AR1 2786/4885 |
| US-20210009559-A1 | CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS | CRBN, IKZF1, IKZF3 | GPR119 4102/4885CNR1 4032/4885C3AR1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.