Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378317 | 0.80 | HRH3 (0.33) | HRH3 | |
| SCHEMBL21414332 | 0.76 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL8285972 | 0.76 | SIGMAR1 (0.44) | HRH3KDM4E | |
| SCHEMBL16788111 | 0.76 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL19860547 | 0.76 | SIGMAR1 (0.44) | HRH3KDM4E | |
| SCHEMBL20635738 | 0.75 | HRH3 (0.33) | HRH3 | |
| SCHEMBL23612752 | 0.74 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL21397761 | 0.74 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL23114309 | 0.74 | SHBG (0.41) | HRH3KDM4E | |
| SCHEMBL23467566 | 0.74 | SHBG (0.41) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | C4 THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-20210009559-A1 | CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS | C4 THERAPEUTICS, INC. (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | CRBN, IKZF1, IKZF3 | HRH3 4527/4885KDM4E 486/4885 |
| US-20210009559-A1 | CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS | CRBN, IKZF1, IKZF3 | HRH3 4292/4885KDM4E 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.