Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18898190 | 0.87 | DRD2 (0.38) | HRH3KDM4EDRD2DRD3 | |
| SCHEMBL20072405 | 0.83 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL8285972 | 0.79 | SIGMAR1 (0.44) | HRH3KDM4E | |
| SCHEMBL21414332 | 0.79 | HRH3 (0.41) | HRH3KDM4EDRD2DRD3OPRM1 | |
| SCHEMBL19860547 | 0.79 | SIGMAR1 (0.44) | HRH3KDM4E | |
| SCHEMBL16788111 | 0.79 | HRH3 (0.41) | HRH3KDM4EDRD2DRD3OPRM1 | |
| SCHEMBL23467566 | 0.77 | SHBG (0.41) | HRH3KDM4E | |
| SCHEMBL18664004 | 0.77 | HRH3 (0.41) | HRH3KDM4EDRD2DRD3OPRM1 | |
| SCHEMBL25757090 | 0.77 | HRH3 (0.41) | HRH3KDM4EDRD2DRD3OPRM1 | |
| SCHEMBL23114309 | 0.77 | SHBG (0.41) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180207-A1 | TRAF 6 INHIBITORS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2019-09-26 | — | — | WO | disclosed |