SCHEMBL22876141

SCHEMBL22876141

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-c5cccc6oc7ccc(-c8cc9ccccc9c9ccccc89)cc7c56)c4)n3)cc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
CYP11B1 P15538 1/20 0.31
MAPK1 P28482 2/20 0.31
KMT2A Q03164 1/20 0.31
CASP3 P42574 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
TERT O14746 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
TSHR P16473 2/20 0.30
HSD17B10 Q99714 2/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22876383 0.98 CYP11B1 (0.31) CYP11B1MAPK1KMT2ACASP3SENP7
SCHEMBL22876433 0.94 ALDH1A1 (0.33) CYP11B1MAPK1ALDH1A1HPGDTSHR
SCHEMBL19802062 0.94 PLA2G10 (0.32) PLA2G10PLA2G2APLA2G4ACYP11B1MAPK1
SCHEMBL22876575 0.93 MAPK1 (0.33) PLA2G10PLA2G2APLA2G4AMAPK1KMT2A
SCHEMBL19802468 0.93 MAPK1 (0.34) PLA2G10PLA2G2APLA2G4AMAPK1KMT2A
SCHEMBL19803062 0.93 CYP11B1 (0.31) CYP11B1MAPK1KMT2ACASP3SENP7
SCHEMBL19802078 0.92 PLA2G2A (0.35) PLA2G10PLA2G2APLA2G4ACASP3SENP7
SCHEMBL24215934 0.92 MEN1 (0.33) PLA2G10PLA2G2APLA2G4AKMT2ACASP3
SCHEMBL19802757 0.92 PLA2G10 (0.31) PLA2G10PLA2G2APLA2G4ACYP11B1CASP3
SCHEMBL19802080 0.91 CASP3 (0.32) PLA2G10PLA2G2APLA2G4ACASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-11685859-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20210009894-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed