Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22877004 | 0.81 | MEN1 (0.30) | — | |
| SCHEMBL16067425 | 0.80 | RAPGEF4 (0.43) | GAALMNAHPGD | |
| SCHEMBL14850897 | 0.78 | RAPGEF4 (0.43) | GAALMNATP53TDP1 | |
| SCHEMBL22877096 | 0.77 | ALDH1A1 (0.35) | GAAHPGDTDP1 | |
| SCHEMBL22877003 | 0.75 | ALDH1A1 (0.32) | GAAHPGD | |
| SCHEMBL23018133 | 0.73 | HPGD (0.38) | GAALMNAGFERHPGD | |
| SCHEMBL22365614 | 0.73 | MEN1 (0.47) | GFERHPGDTDP1 | |
| SCHEMBL14100633 | 0.72 | TDP1 (0.38) | LMNAHPGDTP53TDP1 | |
| SCHEMBL23616124 | 0.71 | CLCN2 (0.44) | GAAGFERHPGD | |
| SCHEMBL14201368 | 0.71 | TDP1 (0.36) | GAALMNAHPGDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | disclosed |