Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 16/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 16/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429478 | 0.94 | LTB4R (0.52) | LTB4RLTB4R2RIPK1PSMB5 | |
| SCHEMBL26429681 | 0.89 | LTB4R (0.54) | LTB4RLTB4R2RIPK1PSMB5 | |
| SCHEMBL22877159 | 0.85 | LTB4R (0.42) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL22877204 | 0.84 | POLB (0.40) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL26429346 | 0.84 | CYP2D6 (0.39) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL22877375 | 0.84 | POLB (0.40) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL22877362 | 0.82 | SLC6A2 (0.38) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL26429440 | 0.81 | CYP2D6 (0.40) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL26704684 | 0.80 | ALDH1A1 (0.39) | LTB4RLTB4R2PSMB5 | |
| SCHEMBL26705039 | 0.79 | POLB (0.39) | LTB4RLTB4R2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339879-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | NORTHWESTERN UNIVERSITY | 2023-10-26 | — | — | US | disclosed |
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | NORTHWESTERN UNIVERSITY (US) | 2023-05-02 | — | — | US | disclosed |
| US-20210009547-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | NORTHWESTERN UNIVERSITY (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009547-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | TYR, ME1, PNPO | LTB4R 401/4885LTB4R2 549/4885RIPK1 4319/4885 |
| US-11639340-B2 | Substituted chromanes, analogs thereof, and methods of use and synthesis | TYR, ME1, PNPO | LTB4R 401/4885LTB4R2 549/4885RIPK1 4319/4885 |
| US-20230339879-A1 | SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS | TYR, ME1, PNPO | LTB4R 401/4885LTB4R2 549/4885RIPK1 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.