Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 1.00 |
| ▸ | TPO | P07202 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280952 | 1.00 | MPO (1.00) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL1960671 | 1.00 | MPO (1.00) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL1461291 | 0.82 | MPO (0.70) | MPOTPOALDH1A1HSD17B10PDE4A | |
| SCHEMBL1460900 | 0.81 | MPO (0.69) | MPOTPOALDH1A1HSD17B10KDM4E | |
| SCHEMBL29084974 | 0.76 | MPO (0.61) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL1962177 | 0.75 | MPO (0.59) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL3256669 | 0.75 | MPO (0.59) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL1959309 | 0.72 | MPO (0.56) | MPOTPOALDH1A1POLBHSD17B10 | |
| SCHEMBL10180927 | 0.71 | MPO (0.60) | MPOTPOHSD17B10PDE4AADORA2A | |
| SCHEMBL1373494 | 0.71 | PDE4A (0.74) | MPOTPOHSD17B10PDE4AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435292-B2 | Anti-corrosive lubricant composition for electrical apparatus | HENKEL AG & CO. KGAA (DE) | 2025-10-07 | — | — | US | claimed |
| US-12383158-B2 | Detection of high-risk unstable atherosclerotic plaque | THE HEART RESEARCH INSTITUTE LTD (AU) | 2025-08-12 | — | — | US | claimed |
| CN-120137627-A | Paraffin asphalt double-effect composite blocking remover and preparation method thereof | 西南石油大学 | 2025-06-13 | — | — | CN | claimed |
| EP-4479498-A1 | ANTI-CORROSIVE LUBRICANT COMPOSITION FOR ELECTRICAL APPARATUS | Henkel AG & Co. KGaA (DE) | 2024-12-25 | — | — | EP | claimed |
| US-20240392205-A1 | ANTI-CORROSIVE LUBRICANT COMPOSITION FOR ELECTRICAL APPARATUS | HENKEL AG & CO. KGAA (DE) | 2024-11-28 | — | — | US | claimed |
| CN-118715309-A | Corrosion resistant lubricating oil composition for electrical equipment | 汉高股份有限及两合公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118531636-A | High-temperature-resistant emulsion sizing agent and preparation method and application thereof | 中复神鹰碳纤维股份有限公司 | 2024-08-23 | — | — | CN | claimed |
| US-20240138701-A1 | DETECTION OF HIGH-RISK UNSTABLE ATHEROSCLEROTIC PLAQUE | THE HEART RESEARCH INSTITUTE LTD (AU) | 2024-05-02 | — | — | US | claimed |
| WO-2024031149-A1 | METHODS FOR THE DETECTION OF MYELOPEROXIDASE | THE UNIVERSITY OF SYDNEY (AU) | 2024-02-15 | — | — | WO | claimed |
| CN-116770591-A | Polyetherimide aqueous emulsion sizing agent, preparation method thereof and carbon fiber | 中复神鹰碳纤维股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| US-20220160715-A1 | MPO INHIBITORS FOR USE IN MEDICINE | ASTRAZENECA AB (SE) | 2022-05-26 | — | — | US | claimed |
| CN-113249095-B | Preparation method of double-layer shell nano microcapsule with energy storage and anticorrosion functions | 上海儒熵新能源科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114257186-A | 5G millimeter wave radio frequency power amplifier based on efficient DPD predistortion algorithm | 蒋永彬 | 2022-03-29 | — | — | CN | claimed |
| US-11246870-B2 | MPO inhibitors for use in medicine | ASTRAZENCA AB (SE) | 2022-02-15 | — | — | US | claimed |
| US-20210298611-A1 | DETECTION OF HIGH-RISK UNSTABLE ATHEROSCLEROTIC PLAQUE | VICTOR CHANG CARDIAC RES INSTITUTE (AU) | 2021-09-30 | — | — | US | claimed |
| US-20200206226-A1 | MPO INHIBITORS FOR USE IN MEDICINE | ASTRAZENECA AB (SE) | 2020-07-02 | — | — | US | claimed |
| EP-3654983-A1 | MPO INHIBITORS FOR USE IN MEDICINE | Astrazeneca AB (SE) | 2020-05-27 | — | — | EP | claimed |
| CN-110891572-A | MPO inhibitors for use in medicine | 阿斯利康(瑞典)有限公司 | 2020-03-17 | — | — | CN | claimed |
| WO-2019016074-A1 | MPO INHIBITORS FOR USE IN MEDICINE | ASTRAZENECA AB (SE) | 2019-01-24 | — | — | WO | claimed |
| US-20080312311-A1 | Crystalline forms of 3-(2R-tetrahydrofuryl-methyl)-2-thioxanthine | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206226-A1 | MPO INHIBITORS FOR USE IN MEDICINE | MPO, SERPINB1, MMP8 | MPO 1/4885TPO 23/4885ALDH1A1 466/4885 |
| US-11246870-B2 | MPO inhibitors for use in medicine | MPO, SERPINB1, MMP8 | MPO 1/4885TPO 23/4885ALDH1A1 466/4885 |
| US-20220160715-A1 | MPO INHIBITORS FOR USE IN MEDICINE | MPO, SERPINB1, MMP8 | MPO 1/4885TPO 23/4885ALDH1A1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.