Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348281 | 0.80 | HRH4 (0.38) | PAOXEPHX1MEN1GLACYP2C19 | |
| SCHEMBL13354516 | 0.77 | PKM (0.34) | PAOXEPHX1KISS1R | |
| SCHEMBL21466313 | 0.76 | LMNA (0.40) | — | |
| SCHEMBL9238486 | 0.76 | KMT2A (0.38) | PAOXEPHX1MEN1CYP2C19KMT2A | |
| SCHEMBL19104227 | 0.76 | CA12 (0.48) | PAOXMEN1CYP2C19KMT2A | |
| SCHEMBL21466314 | 0.74 | LMNA (0.44) | — | |
| SCHEMBL24508702 | 0.73 | EPHX1 (0.46) | PAOXEPHX1KISS1R | |
| SCHEMBL25557251 | 0.73 | EPHX1 (0.46) | PAOXEPHX1KISS1R | |
| SCHEMBL25832099 | 0.73 | EPHX1 (0.46) | PAOXEPHX1KISS1R | |
| SCHEMBL3024820 | 0.73 | CYP2C19 (0.53) | PAOXEPHX1MEN1GLACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3096751-B1 | 12-EPI-PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2021-01-06 | — | — | EP | disclosed |