Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 14/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886453 | 0.91 | EPHX2 (0.45) | EPHX2CAPN1GRM5 | |
| SCHEMBL22886452 | 0.82 | EPHX2 (0.42) | EPHX2GRM5 | |
| SCHEMBL22886543 | 0.81 | L3MBTL1 (0.46) | CAPN1 | |
| SCHEMBL22885869 | 0.79 | CAPN1 (0.40) | CAPN1 | |
| SCHEMBL22886426 | 0.78 | FTO (0.42) | CAPN1 | |
| SCHEMBL22886593 | 0.78 | CAPN1 (0.36) | CAPN1 | |
| SCHEMBL20027860 | 0.73 | CAPN1 (0.52) | CAPN1 | |
| SCHEMBL22886508 | 0.73 | CAPN1 (0.45) | CAPN1 | |
| SCHEMBL22886730 | 0.73 | L3MBTL1 (0.41) | CAPN1 | |
| SCHEMBL22886544 | 0.72 | L3MBTL1 (0.44) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPERTICS INC (US) | 2021-01-14 | — | — | US | disclosed |
| CN-112204014-A | Calpain modulators and therapeutic uses thereof | 布莱德治疗公司 | 2021-01-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | EPHX2 4376/4885CAPN1 3/4885GRM5 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.