Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.48 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028717 | 0.91 | DCAF1 (0.50) | PYGLDCAF1TACR3CTSVCTSL | |
| SCHEMBL20027723 | 0.91 | PYGL (0.52) | PYGLDCAF1TACR3CTSVCTSL | |
| SCHEMBL22885979 | 0.84 | PYGL (0.46) | PYGLDCAF1TACR3CTSLKMT2A | |
| SCHEMBL22886636 | 0.83 | DCAF1 (0.48) | DCAF1TACR3CTSVCTSLCTSS | |
| SCHEMBL29961519 | 0.83 | DCAF1 (0.48) | DCAF1TACR3CTSVCTSLCTSS | |
| SCHEMBL21854327 | 0.82 | DCAF1 (0.53) | DCAF1CTSVCTSLCTSSCTSK | |
| SCHEMBL20027495 | 0.82 | DCAF1 (0.53) | DCAF1CTSVCTSLCTSSCTSK | |
| SCHEMBL20027718 | 0.82 | DCAF1 (0.51) | PYGLDCAF1CTSVCTSLCTSS | |
| SCHEMBL22897243 | 0.82 | DCAF1 (0.51) | PYGLDCAF1CTSVCTSLCTSS | |
| SCHEMBL22886629 | 0.82 | DCAF1 (0.50) | DCAF1TACR3CTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPERTICS INC (US) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009564-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN9, CAPN1 | PYGL 719/4885DCAF1 2355/4885TACR3 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.