Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 12/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423338 | 0.81 | CCR1 (0.56) | DYRK1ANFATC1MAP4K4WNT3APSEN1 | |
| SCHEMBL1492636 | 0.79 | MAP4K4 (0.50) | DYRK1ANFATC1MAP4K4WNT3APSEN1 | |
| SCHEMBL18015428 | 0.79 | MAP4K4 (0.43) | DYRK1ANFATC1MAP4K4WNT3APSEN1 | |
| SCHEMBL27861147 | 0.76 | WNT3A (0.52) | MAP4K4WNT3APSEN1PSEN2APH1B | |
| SCHEMBL25308859 | 0.75 | KDM4E (0.46) | MAP4K4WNT3APSEN1PSEN2APH1B | |
| SCHEMBL1912416 | 0.75 | WNT3A (0.51) | MAP4K4WNT3APSEN1PSEN2APH1B | |
| SCHEMBL17051593 | 0.75 | CYP3A4 (0.54) | DYRK1AWNT3AUHRF1 | |
| SCHEMBL23474083 | 0.74 | HPGDS (0.41) | — | |
| SCHEMBL22885537 | 0.74 | WNT3A (0.43) | DYRK1ANFATC1WNT3AUHRF1 | |
| SCHEMBL1896511 | 0.73 | DYRK1A (0.65) | DYRK1ANFATC1MAP4K4WNT3APSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004467-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | 南京明德新药研发有限公司 | 2021-01-14 | — | — | WO | disclosed |