Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890855 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22889894 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL27170662 | 0.63 | L3MBTL1 (0.36) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL29493825 | 0.63 | L3MBTL1 (0.36) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL25613932 | 0.61 | AR (0.42) | ALDH1A1KDM4E | |
| SCHEMBL14825309 | 0.60 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL23269411 | 0.59 | L3MBTL1 (0.50) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29659097 | 0.59 | L3MBTL1 (0.54) | ALDH1A1KDM4ECYP1A2CYP2C19KMT2A | |
| SCHEMBL30586208 | 0.59 | L3MBTL1 (0.50) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14967240 | 0.59 | L3MBTL1 (0.54) | ALDH1A1KDM4ECYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007477-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |