Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27170662 | 0.79 | L3MBTL1 (0.36) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL29493825 | 0.79 | L3MBTL1 (0.36) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL11822208 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL31184166 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL13329219 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL22889897 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C9 | |
| SCHEMBL25613932 | 0.73 | AR (0.42) | ALDH1A1KDM4EHTTGLAGAA | |
| SCHEMBL22889894 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL14825309 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL19024184 | 0.73 | L3MBTL1 (0.37) | ALDH1A1KDM4EL3MBTL1HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007477-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2021-01-14 | — | — | WO | disclosed |