Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 11/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28708945 | 0.86 | MDM2 (0.40) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22892703 | 0.86 | MDM2 (0.40) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7267896 | 0.84 | ADORA3 (0.58) | KLK5ACEF2PRSS1ADORA3 | |
| SCHEMBL7276997 | 0.82 | ADORA3 (0.57) | KLK5ACEF2PRSS1ADORA3 | |
| SCHEMBL9462716 | 0.82 | ADORA3 (0.61) | KLK5ACEF2PRSS1ADORA3 | |
| SCHEMBL21838235 | 0.80 | PRCP (0.46) | KLK5ACEPRCPCMA1 | |
| SCHEMBL21838233 | 0.80 | PRCP (0.46) | KLK5ACEPRCPCMA1 | |
| SCHEMBL21838236 | 0.80 | PRCP (0.46) | KLK5ACEPRCPCMA1 | |
| SCHEMBL30058495 | 0.80 | PRCP (0.46) | KLK5ACEPRCPCMA1 | |
| SCHEMBL30849154 | 0.80 | ACE (0.47) | ACEPRCPCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3792250-A1 | SYNTHESIS OF ALPHA-AMANITIN AND ITS DERIVATIVES | Pure Bioorganics SIA (LV) | 2021-03-17 | — | — | EP | disclosed |
| WO-2021004973-A1 | SYNTHESIS OF A-AMANITIN AND ITS DERIVATIVES | PURE BIOORGANICS SIA (LV) | 2021-01-14 | — | — | WO | disclosed |