Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 14/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267896 | 0.97 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL9462716 | 0.93 | ADORA3 (0.61) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL30859278 | 0.89 | KLK5 (0.55) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL25133623 | 0.89 | KLK5 (0.55) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL9351673 | 0.89 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL38652049 | 0.88 | ACE (0.54) | ADORA3ADORA2AADORA2BADORA1CMA1 | |
| SCHEMBL10403794 | 0.87 | ACE (0.56) | CMA1F2PRSS1KLK5ACE | |
| SCHEMBL7537159 | 0.87 | ACE (0.63) | CMA1F2PRSS1KLK5ACE | |
| SCHEMBL7148899 | 0.87 | ACE (0.63) | CMA1F2PRSS1KLK5ACE | |
| SCHEMBL8364102 | 0.85 | ACE (0.54) | CMA1F2PRSS1KLK5CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345867-B1 | NOVEL SYNTHETIC, IMMUNOLOGICALLY ACTIVE PEPTIDES USEFUL FOR THE PREPARATION OF ANTIMALARIAL VACCINES | ENIRICERCHE S.p.A. (IT) | 1993-04-07 | — | — | EP | disclosed |
| EP-0345867-A1 | Novel synthetic, immunologically active peptides useful for the preparation of antimalarial vaccines | ENIRICERCHE S.p.A. (IT) | 1989-12-13 | — | — | EP | disclosed |