SCHEMBL22893170

SCHEMBL22893170

OC1Cc2ccccc2CC1S

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.47
SLC18A3 Q16572 6/20 0.41
IDO1 P14902 2/20 0.38
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29533177 1.00 ANPEP (0.47) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL1990446 0.82 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL29687690 0.82 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL20063792 0.82 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL1990443 0.82 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL11824987 0.82 PLAU (0.48) ANPEPIDO1
SCHEMBL20095994 0.82 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1
Naphthalene SCHEMBL8201172 0.75 ANPEP (0.50) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL21473257 0.74 ANPEP (0.41) ANPEP
SCHEMBL18033732 0.74 ANPEP (0.41) ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634508-B2 Peptide conjugates of cytotoxins as therapeutics Cybrexa 2, Inc. (US) 2023-04-25 US disclosed
US-20210009719-A1 PEPTIDE CONJUGATES OF CYTOTOXINS AS THERAPEUTICS Cybrexa 2, Inc. 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11634508-B2 Peptide conjugates of cytotoxins as therapeutics TOP1, TOP2A, TOP2B ANPEP 29/4885SLC18A3 2141/4885IDO1 2522/4885
US-20210009719-A1 PEPTIDE CONJUGATES OF CYTOTOXINS AS THERAPEUTICS TOP1, TOP2A, TOP2B ANPEP 29/4885SLC18A3 2141/4885IDO1 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.