Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530694 | 0.74 | TTR (0.48) | CA2CA4TDP1ACHECYP3A4 | |
| SCHEMBL14394922 | 0.74 | ACHE (0.55) | CA2CA4TDP1ACHECYP3A4 | |
| SCHEMBL210358 | 0.72 | ACHE (0.59) | ACHECYP3A4MAPTCA9ALDH1A1 | |
| SCHEMBL4599330 | 0.72 | ACHE (0.40) | CA2CA4TDP1ACHECYP3A4 | |
| SCHEMBL13369758 | 0.72 | CA2 (0.42) | CA2CA4TDP1ACHECYP3A4 | |
| SCHEMBL15998071 | 0.72 | TPMT (0.37) | TDP1ACHECYP3A4MAPTCA9 | |
| SCHEMBL17110036 | 0.70 | ALDH1A1 (0.44) | CA2CA4TDP1ACHETPMT | |
| SCHEMBL3358050 | 0.70 | PDGFRB (0.37) | CA2CA4TDP1ACHECYP3A4 | |
| SCHEMBL2398559 | 0.70 | CA2 (0.58) | CA2CA4TDP1ACHEMAPT | |
| SCHEMBL12440995 | 0.67 | TTR (0.40) | CA2CA4TDP1ACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601436-B1 | FLAME-RETARDED STYRENE-CONTAINING FORMULATIONS | BROMINE COMPOUNDS LTD (IL) | 2021-01-13 | — | — | EP | disclosed |