Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 8/20 | 0.61 |
| ▸ | KCNJ3 | P48549 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15741662 | 0.84 | ROCK2 (0.66) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL19576804 | 0.83 | KCNJ5 (0.62) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL24685908 | 0.82 | KCNJ5 (0.61) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL24687034 | 0.82 | KCNJ5 (0.61) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL29718827 | 0.81 | P2RX4 (0.71) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL19552065 | 0.81 | P2RX4 (0.71) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL19576469 | 0.81 | ALDH1A1 (0.77) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL19576873 | 0.81 | KCNJ5 (0.60) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL15741746 | 0.80 | KCNJ5 (0.68) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA | |
| SCHEMBL24686766 | 0.80 | MEN1 (0.57) | KCNJ5KCNJ3ALDH1A1KCNJ6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021092-A1 | STRUCTURE-BASED DESIGN OF A NOVEL CLASS OF DRUGS FOR NEURODEGENERATIVE DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021092-A1 | STRUCTURE-BASED DESIGN OF A NOVEL CLASS OF DRUGS FOR NEURODEGENERATIVE DISEASE | SNCA, MAPT, PSEN2 | KCNJ5 4568/4885KCNJ3 4716/4885ALDH1A1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.