Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.61 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.61 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24685908 | 0.90 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL24687088 | 0.85 | ROCK2 (0.49) | KCNJ5KCNJ3ALDH1A1LMNAMEN1 | |
| SCHEMBL24687094 | 0.83 | ANO1 (0.52) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL24686768 | 0.83 | P2RX4 (0.69) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL24686362 | 0.82 | SMN1; SMN2 (0.58) | LMNAMEN1KMT2AP2RX4POLB | |
| SCHEMBL32664293 | 0.82 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL24686639 | 0.81 | KCNJ5 (0.55) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL15741746 | 0.80 | KCNJ5 (0.68) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL24686766 | 0.80 | MEN1 (0.57) | KCNJ5KCNJ3KCNJ6CLK2PRKX | |
| SCHEMBL24686674 | 0.80 | KCNJ5 (0.54) | KCNJ5KCNJ3KCNJ6CLK2PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |