Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 6/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22353143 | 0.84 | KCNJ5 (0.44) | KCNJ5KCNJ3KCNJ6PGRROCK2 | |
| SCHEMBL19552082 | 0.83 | P2RX4 (0.55) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL29716936 | 0.83 | P2RX4 (0.55) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL22353153 | 0.78 | ROCK2 (0.45) | KCNJ5KCNJ3KCNJ6ROCK2ROCK1 | |
| SCHEMBL22353142 | 0.77 | KCNJ5 (0.49) | KCNJ5KCNJ3KCNJ6PGRALDH1A1 | |
| SCHEMBL19552117 | 0.76 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19551492 | 0.76 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL22894150 | 0.75 | KCNJ5 (0.55) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL22353212 | 0.73 | KCNJ5 (0.49) | KCNJ5KCNJ3KCNJ6ROCK2ROCK1 | |
| SCHEMBL22353144 | 0.73 | NPC1 (0.48) | KCNJ5KCNJ3KCNJ6ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763704-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2021-01-13 | — | — | EP | disclosed |