Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907356 | 0.77 | SMN1; SMN2 (0.36) | TP53MAPTLMNAHPGDTSHR | |
| SCHEMBL17907311 | 0.76 | MAPT (0.37) | MAPTLMNATSHRL3MBTL1 | |
| SCHEMBL22894548 | 0.75 | SMN1; SMN2 (0.49) | TP53MAPTLMNAHPGDTSHR | |
| SCHEMBL30931022 | 0.73 | SCN9A (0.36) | MAPT | |
| SCHEMBL30931056 | 0.71 | MEN1 (0.46) | MAPTLMNAHPGDTSHRP2RX7 | |
| SCHEMBL22894543 | 0.71 | MEN1 (0.46) | MAPTLMNAHPGDTSHRP2RX7 | |
| SCHEMBL30931180 | 0.68 | SCN9A (0.33) | MAPTP2RX7 | |
| SCHEMBL19308363 | 0.66 | PARP1 (0.33) | — | |
| SCHEMBL1145124 | 0.64 | ALDH1A1 (0.49) | TP53MAPTLMNAHPGDTSHR | |
| SCHEMBL19297530 | 0.64 | RAB9A (0.45) | TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042907-B1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | QUINGDAO HUANGHAI PHARMACEUTICAL CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |