Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348971 | 0.91 | CCR1 (0.39) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL8302887 | 0.84 | CA12 (0.55) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL30931056 | 0.83 | MEN1 (0.46) | SCN9ASCN10APARP1ALDH1A1HPGD | |
| SCHEMBL22894543 | 0.83 | MEN1 (0.46) | SCN9ASCN10APARP1ALDH1A1HPGD | |
| SCHEMBL22542026 | 0.83 | SCN9A (0.43) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL22894540 | 0.81 | P2RX7 (0.39) | SCN9ASCN10ATSHRMAPTSRD5A1 | |
| SCHEMBL22894548 | 0.80 | SMN1; SMN2 (0.49) | SCN9ASCN10APARP1ALDH1A1HPGD | |
| SCHEMBL24478480 | 0.79 | PARP1 (0.46) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL24451807 | 0.79 | SCN9A (0.41) | SCN9ASCN10ACA12CA1CA2 | |
| SCHEMBL30931022 | 0.79 | SCN9A (0.36) | SCN9ASCN10APARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |
| EP-3042907-B1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | QUINGDAO HUANGHAI PHARMACEUTICAL CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |