SCHEMBL22895263

SCHEMBL22895263

[N-]=[N+]=NCCOCCOCCCN

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGMT P16455 1/20 0.36
ODC1 P11926 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23571410 0.98 ODC1 (0.35) MGMTODC1
SCHEMBL23226055 0.94 MGMT (0.36) MGMT
SCHEMBL13658545 0.91 ODC1 (0.33) MGMTODC1
SCHEMBL25755568 0.89 ODC1 (0.35) ODC1
SCHEMBL25756204 0.87 ODC1 (0.33) ODC1
SCHEMBL14330842 0.86 MGMT (0.41) MGMT
SCHEMBL16329221 0.86 MGMT (0.41) MGMT
SCHEMBL13449873 0.86 MGMT (0.41) MGMT
SCHEMBL13612332 0.86 MGMT (0.41) MGMT
SCHEMBL13497925 0.86 MGMT (0.41) MGMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed
US-10894091-B2 Linker units and molecular constructs comprising the same Immunwork Inc. (TW) 2021-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 MGMT 4434/4885ODC1 4097/4885
US-10894091-B2 Linker units and molecular constructs comprising the same CD2BP2, BCR, UACA MGMT 2288/4885ODC1 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.