Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 11/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | YTHDF3 | Q7Z739 | 2/20 | 0.32 |
| ▸ | YTHDF1 | Q9BYJ9 | 2/20 | 0.32 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30733376 | 0.76 | YTHDC1 (0.42) | XDHYTHDC1PDE2AMETAP2METAP1 | |
| SCHEMBL20111045 | 0.76 | YTHDC1 (0.42) | XDHYTHDC1PDE2AMETAP2METAP1 | |
| SCHEMBL30712146 | 0.73 | YTHDC1 (0.40) | XDHYTHDC1PDE2AMETAP2METAP1 | |
| SCHEMBL16094334 | 0.70 | YTHDC1 (0.61) | XDHYTHDC1PDE2ACYP1A2PDE4A | |
| SCHEMBL11360668 | 0.70 | YTHDC1 (0.38) | XDHYTHDC1PDE2ALMNACYP1A2 | |
| SCHEMBL22895988 | 0.67 | ALDH1A1 (0.39) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL26794545 | 0.67 | YTHDC1 (0.36) | XDHYTHDC1PDE2APDE4A | |
| SCHEMBL21230675 | 0.66 | PDE2A (0.41) | XDHYTHDC1PDE2ALMNACYP1A2 | |
| SCHEMBL25166582 | 0.65 | YTHDC1 (0.46) | XDHYTHDC1PDE2AMETAP2METAP1 | |
| SCHEMBL30329676 | 0.65 | YTHDC1 (0.46) | XDHYTHDC1PDE2AMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358958-B2 | — | — | 2022-06-14 | — | — | US | disclosed |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. | 2021-05-06 | — | — | US | disclosed |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | KINNATE BIOPHARMA INC. (US) | 2021-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358958-B2 | — | CDK2, CDK1, CDK6 | XDH 2347/4885YTHDC1 4725/4885PDE2A 2743/4885 |
| US-20210130340-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | CDK2, CCNK, CDK1 | XDH 2602/4885YTHDC1 4714/4885PDE2A 3038/4885 |
| US-10894788-B2 | Inhibitors of cyclin-dependent kinases | CDK2, CCNK, CDK1 | XDH 2602/4885YTHDC1 4714/4885PDE2A 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.