Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 7/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.30 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.30 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111045 | 1.00 | YTHDC1 (0.42) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL30712146 | 0.76 | YTHDC1 (0.40) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL30712154 | 0.76 | PTPN1 (0.39) | PGK1METAP2METAP1TDP1 | |
| SCHEMBL22895601 | 0.76 | XDH (0.43) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL11033453 | 0.76 | YTHDC1 (0.40) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL10511271 | 0.75 | KDM4E (0.36) | CYP1A2ALDH1A1ALOX15TSHRGAA | |
| SCHEMBL16094334 | 0.74 | YTHDC1 (0.61) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL22843514 | 0.73 | YTHDC1 (0.38) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL11360668 | 0.73 | YTHDC1 (0.38) | YTHDC1XDHPDE2ACYP1A2PDE4A | |
| SCHEMBL10990838 | 0.73 | XDH (0.41) | YTHDC1XDHPDE2APGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425660-A | Aromatic heterocyclic compound, intermediate thereof, pharmaceutical composition and application | 上海翊石医药科技有限公司 | 2024-01-19 | — | — | CN | disclosed |