SCHEMBL2289603

SCHEMBL2289603

CC(C(=O)Oc1ccccc1)C(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.64
ATM Q13315 2/20 0.64
ELANE P08246 4/20 0.50
TDP1 Q9NUW8 2/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
CDK5 Q00535 1/20 0.40
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24634130 0.90 ATM (0.53) L3MBTL1ATMELANETDP1MAPT
SCHEMBL11451065 0.83 ATM (0.53) L3MBTL1ATMELANETDP1MAPT
SCHEMBL2308308 0.83 ATM (0.53) L3MBTL1ATMELANETDP1LMNA
SCHEMBL24850059 0.82 L3MBTL1 (0.66) L3MBTL1ATMELANETDP1MAPT
SCHEMBL19932805 0.82 CYP3A4 (0.59) L3MBTL1ATMLMNAMEN1KMT2A
SCHEMBL6220966 0.81 ATM (0.51) L3MBTL1ATMELANETDP1MAPT
SCHEMBL19544862 0.81 L3MBTL1 (0.51) L3MBTL1ATMELANETDP1MAPT
SCHEMBL5853099 0.80 ATM (0.50) L3MBTL1ATMELANETDP1LMNA
SCHEMBL19105361 0.80 ATM (0.58) L3MBTL1ATMELANETDP1MAPT
SCHEMBL2294888 0.80 ATM (0.58) L3MBTL1ATMELANETDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP claimed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US claimed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO claimed
US-11732223-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc (US) 2023-08-22 US disclosed
US-11001789-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc. (US) 2021-05-11 US disclosed
US-20180037850-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof CRUDE SPILL CLEANING COMPANY, INC. 2018-02-08 US disclosed
US-9512155-B2 Chiral phosphines for palladium-catalyzed asymmetric α-arylation of ester enolates to produce tertiary stereocenters in high enantioselectivity NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-12-06 US disclosed
US-20160311785-A1 TRIAZINE MEDIATED LIVING RADICAL CONTROLLED POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC 2016-10-27 US disclosed
US-20150166586-A1 CHIRAL PHOSPHINES FOR PALLADIUM-CATALYZED ASYMMETRIC ALPHA-ARYLATION OF ESTER ENOLATES TO PRODUCE TERTIARY STEREOCENTERS IN HIGH ENANTIOSELECTIVITY NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2015-06-18 US disclosed
US-20150152363-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof TROXLER ELECTRONIC LABORATORIES, INC. 2015-06-04 US disclosed
US-8951952-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof TROXLER ELECTRONIC LABORATORIES, INC. (US) 2015-02-10 US disclosed
US-7465395-B2 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY (US) 2008-12-16 US disclosed
EP-1723224-A4 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LAB INC (US) 2008-02-27 EP disclosed
US-20070095753-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents CARBONELL RUBEN G 2007-05-03 US disclosed
EP-1723224-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF Troxler Electronics Laboratories, Inc. (US) 2006-11-22 EP disclosed
WO-2005091771-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-10-06 WO disclosed
US-20050197267-A1 10-60% by weight aromatic ester, 30-60% by weight aliphatic ester, 0-15% by weight co-solvent, 0-10% by weight cyclic terpene or terpenoid, 0-1% by weight odor-masking agent and 0-20% by weight nonionic surfactant; for removing petroleum residues (e.g., asphalt) from work surface such as truck bed TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-09-08 US disclosed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP disclosed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US disclosed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166586-A1 CHIRAL PHOSPHINES FOR PALLADIUM-CATALYZED ASYMMETRIC ALPHA-ARYLATION OF ESTER ENOLATES TO PRODUCE TERTIARY STEREOCENTERS IN HIGH ENANTIOSELECTIVITY EPHA8, DAGLA, TEC L3MBTL1 129/4885ATM 3703/4885ELANE 287/4885
US-20160311785-A1 TRIAZINE MEDIATED LIVING RADICAL CONTROLLED POLYMERIZATION ROS1, MTR, CYBB L3MBTL1 3393/4885ATM 2747/4885ELANE 4466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.