Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.32 |
| ▸ | HTR2C | P28335 | 6/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292775 | 0.91 | SCN9A (0.36) | SCN9AALOX5APFEN1L3MBTL1STK17B | |
| SCHEMBL1711953 | 0.87 | MTNR1A (0.39) | SCN9APCSK9GRM2MTNR1AMTNR1B | |
| SCHEMBL2292765 | 0.85 | ROCK2 (0.36) | SCN9A | |
| SCHEMBL2287233 | 0.85 | SCN9A (0.34) | SCN9APCSK9ALOX5APFEN1L3MBTL1 | |
| SCHEMBL1724180 | 0.79 | KCNH2 (0.43) | SCN9AKCNH2 | |
| SCHEMBL1711943 | 0.78 | MTNR1A (0.42) | SCN9AMTNR1AMTNR1BHTR2CL3MBTL1 | |
| SCHEMBL1712060 | 0.75 | MTNR1A (0.40) | SCN9APCSK9MTNR1AMTNR1BHTR2C | |
| SCHEMBL1712486 | 0.73 | MTNR1A (0.39) | SCN9APCSK9MTNR1AMTNR1BHTR2C | |
| SCHEMBL15707804 | 0.71 | KCNH2 (0.41) | SCN9AMTNR1AMTNR1BKCNH2 | |
| SCHEMBL1712057 | 0.71 | PTGS2 (0.38) | SCN9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618092-B2 | Tricyclic oxazolidinone antibiotic compounds | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-12-31 | — | — | US | disclosed |
| US-20110195961-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195961-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | HRH3, OXA1L, HRH1 | SCN9A 458/4885PCSK9 1965/4885ALOX5AP 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.