Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886847 | 0.83 | PNMT (0.56) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL540925 | 0.82 | SLC6A4 (0.52) | EPHX1PYGLLAP3ANPEPRNPEP | |
| SCHEMBL26431200 | 0.79 | EPHX1 (0.46) | EPHX1IDO1HTR3EHTR3BHTR3A | |
| SCHEMBL20027620 | 0.79 | EPHX1 (0.43) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL28306039 | 0.77 | EPHX1 (0.42) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL10772763 | 0.74 | SLC15A1 (0.56) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL4619659 | 0.74 | SLC15A1 (0.56) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6342154 | 0.74 | SLC15A1 (0.56) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL289159 | 0.74 | SLC15A1 (0.56) | EPHX1LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL10775336 | 0.73 | SLC15A1 (0.54) | EPHX1LAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-10894776-B2 | — | — | 2021-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | EPHX1 4200/4885IDO1 4798/4885HTR3E 2960/4885 |
| US-10894776-B2 | — | CAPNS1, CAPN9, CAPN2 | EPHX1 4249/4885IDO1 4761/4885HTR3E 2038/4885 |
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | EPHX1 4200/4885IDO1 4798/4885HTR3E 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.