SCHEMBL22897732

SCHEMBL22897732

CCCN(CCC)c1ccc(C(C)C)c(N)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.40
CASR P41180 1/20 0.36
AR P10275 2/20 0.35
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 2/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
PSMD14 O00487 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
GFER P55789 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPSR1 Q6W5P4 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPBWR1 P48145 1/20 0.33
MCHR1 Q99705 1/20 0.33
IGLV6-57 P01721 1/20 0.33
MAPT P10636 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559520 1.00 S100B (0.40) S100BCASRARALDH1A1L3MBTL1
SCHEMBL22897580 0.86 S100B (0.55) S100BALDH1A1L3MBTL1MAPK1PSMD14
SCHEMBL29559798 0.86 S100B (0.55) S100BALDH1A1L3MBTL1MAPK1PSMD14
SCHEMBL3288762 0.77 S100B (0.52) S100BARALDH1A1L3MBTL1MAPK1
SCHEMBL12674065 0.76 ALDH1A1 (0.43) ALDH1A1L3MBTL1MAPK1CYP3A4TSHR
SCHEMBL12674293 0.75 ADORA2A (0.39) ALDH1A1TDP1KDM4E
SCHEMBL7100535 0.73 S100B (0.72) S100BARALDH1A1L3MBTL1MAPK1
SCHEMBL22897746 0.72 AAK1 (0.37) ALDH1A1L3MBTL1SMN1; SMN2NPBWR1MCHR1
SCHEMBL29559244 0.72 AAK1 (0.37) ALDH1A1L3MBTL1SMN1; SMN2NPBWR1MCHR1
SCHEMBL21031712 0.72 S100B (0.43) S100BARALDH1A1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed