SCHEMBL22897747

SCHEMBL22897747

CCN(C(C)=O)c1ccc(C(C)C)c(N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
RXRA P19793 6/20 0.38
RXRB P28702 2/20 0.38
RXRG P48443 2/20 0.38
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2B6 P20813 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MLYCD O95822 1/20 0.34
MET P08581 1/20 0.34
POLQ O75417 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22897709 0.81 AAK1 (0.38) RXRARXRBRXRGHSP90AA1HSP90AB1
SCHEMBL9135996 0.80 TDP1 (0.44) SMN1; SMN2CYP3A4LMNAALDH1A1GLA
SCHEMBL22897762 0.80 ALDH1A1 (0.41) SMN1; SMN2HSP90AA1HSP90AB1LMNAALDH1A1
SCHEMBL14116544 0.78 SMN1; SMN2 (0.41) SMN1; SMN2RXRARXRBRXRGCYP2C9
SCHEMBL22897580 0.77 S100B (0.55) SMN1; SMN2RXRARXRBRXRGCYP3A4
SCHEMBL29559798 0.77 S100B (0.55) SMN1; SMN2RXRARXRBRXRGCYP3A4
SCHEMBL29561034 0.74 SMN1; SMN2 (0.45) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL22897689 0.74 SMN1; SMN2 (0.45) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL22537737 0.74 OXTR (0.45) SMN1; SMN2HSP90AA1HSP90AB1CYP3A4LMNA
SCHEMBL22897746 0.73 AAK1 (0.37) SMN1; SMN2RXRARXRBRXRGHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed