SCHEMBL22897771

SCHEMBL22897771

COCOc1ccc(-n2cnc(Br)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.38
CYP2C9 P11712 4/20 0.38
CYP2D6 P10635 3/20 0.38
CYP2C19 P33261 3/20 0.38
MAPT P10636 3/20 0.37
CYP19A1 P11511 3/20 0.35
NOTUM Q6P988 2/20 0.33
POLB P06746 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
ATF4 P18848 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SENP8 Q96LD8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22897834 0.85 MAPT (0.47) CYP1A2CYP2C9CYP2D6CYP2C19MAPT
SCHEMBL22897465 0.85 CYP1A2 (0.47) CYP1A2CYP2C9MAPTPOLBADORA3
SCHEMBL22660837 0.78 PTGS1 (0.39) CYP1A2CYP2C9CYP2D6CYP2C19MAPT
SCHEMBL17454042 0.77 KMT2A (0.40) MAPTPOLBALDH1A1KMT2A
SCHEMBL16073029 0.75 ALDH1A1 (0.43) MAPTNOTUMPOLBADORA3ALDH1A1
SCHEMBL28701030 0.74 ALDH1A1 (0.42) MAPTALDH1A1PKMMEN1KMT2A
SCHEMBL14577291 0.74 RXRA (0.42) CYP1A2MAPTPOLBALDH1A1
SCHEMBL14617274 0.72 RXRA (0.35) CYP1A2CYP2C9CYP2D6CYP2C19
SCHEMBL3589633 0.72 NQO1 (0.50) CYP2C9MAPTTDP1
SCHEMBL1844349 0.72 NOTUM (0.41) CYP1A2CYP2C9CYP2C19NOTUMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed