Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125680 | 0.75 | GABRA2 (0.40) | GABRA2GABRB2GABRB3 | |
| SCHEMBL22898326 | 0.75 | PDE2A (0.46) | GABRA2GABRB2CNR2CNR1 | |
| SCHEMBL20093566 | 0.74 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL24032161 | 0.71 | GABRA2 (0.34) | GABRA2GABRB2CNR2CNR1 | |
| SCHEMBL19833112 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL23502518 | 0.70 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL8220439 | 0.69 | GABRA2 (0.46) | GABRA2GABRB2GABRB3 | |
| SCHEMBL22024340 | 0.69 | MEN1 (0.41) | — | |
| SCHEMBL24910863 | 0.69 | CNR2 (0.33) | CNR2CNR1 | |
| SCHEMBL20458052 | 0.68 | ESR1 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015100-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015100-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | GART, BROX, APRT | GABRA2 4437/4885GABRB2 3885/4885GABRB3 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.