SCHEMBL22899166

SCHEMBL22899166

C[C@H]1/C=C\C=C/c2cc(N)ccc2C1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22415115 0.88 ALDH1A1 (0.33) NR1H2ALDH1A1HTT
SCHEMBL22416490 0.74 CASP1 (0.35) NR1H2ALDH1A1HTT
SCHEMBL21547203 0.71 ALDH1A1 (0.35) ALDH1A1HTT
SCHEMBL21539909 0.71
SCHEMBL19891915 0.68 ACHE (0.41) ALDH1A1
SCHEMBL24385269 0.67 ACHE (0.36) ALDH1A1HTT
SCHEMBL17612845 0.67 CA12 (0.34) ALDH1A1HTT
SCHEMBL24771873 0.66
SCHEMBL22783033 0.66 DRD1 (0.37) ALDH1A1HTT
SCHEMBL23396540 0.63 MEN1 (0.39) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3461830-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-01-20 EP disclosed