Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373065 | 0.77 | HTR6 (0.51) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL3766233 | 0.76 | DRD2 (0.44) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL1078756 | 0.69 | KDM4E (0.55) | DRD2DRD4HTR6SLC6A4KDM4E | |
| Hydrochloric Acid SCHEMBL2263936 | 0.69 | KDM4E (0.55) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL29387382 | 0.69 | KDM4E (0.55) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL7255363 | 0.69 | HTR6 (0.58) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL23320624 | 0.69 | SLC6A4 (0.45) | HTR6SLC6A4KDM4ELMNAPOLB | |
| SCHEMBL17645768 | 0.68 | QDPR (0.62) | — | |
| SCHEMBL4159466 | 0.68 | KDM4E (0.54) | DRD2DRD4HTR6SLC6A4KDM4E | |
| SCHEMBL1673482 | 0.68 | HTR6 (0.54) | DRD2DRD4HTR6SLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009068-A1 | N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME | SCENIC IMMUNOLOGY B.V. (NL) | 2021-01-21 | — | — | WO | disclosed |