SCHEMBL22901380

SCHEMBL22901380

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nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.46
▸ TUBB1 Q9H4B7 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12202700 0.80 DPP4 (0.40) DPP4
SCHEMBL14567809 0.78 TUBB1 (0.48) TUBB1
SCHEMBL57849 0.78 TUBB1 (0.48) TUBB1
SCHEMBL13751416 0.78 TUBB1 (0.48) TUBB1
SCHEMBL57601 0.74 TUBB1 (0.61) DPP4TUBB1
SCHEMBL16861443 0.73 TUBB1 (0.33) TUBB1
SCHEMBL22643755 0.73 TUBB1 (0.33) TUBB1
SCHEMBL5578335 0.73 TUBB1 (0.33) TUBB1
SCHEMBL16862667 0.73 TUBB1 (0.33) TUBB1
SCHEMBL5578339 0.73 TUBB1 (0.33) TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220047716-A1 COMBINATION THERAPIES WITH ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2022-02-17 — — US disclosed
US-20210017274-A1 Drug-Conjugates With a Targeting Molecule and Two Different Drugs SORRENTO THERAPEUTICS, INC. (US) 2021-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220047716-A1 COMBINATION THERAPIES WITH ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES FOLR1, FOLR2, DHFR DPP4 3375/4885TUBB1 1159/4885
US-20210017274-A1 Drug-Conjugates With a Targeting Molecule and Two Different Drugs ERBB2, ABCG2, DYNLL2 DPP4 2884/4885TUBB1 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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