SCHEMBL22901516

SCHEMBL22901516

O=C1OC(=O)c2cc3c(cc21)Oc1cc2c(cc1C3(c1ccncc1)C(F)(F)F)C(=O)OC2=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.35
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11887457 0.87 TDP1 (0.34) PDK2
SCHEMBL22901506 0.86 TDP2 (0.35)
SCHEMBL22901514 0.85 PDK2 (0.36) ABL1PDK2
SCHEMBL11887458 0.84 TP53 (0.33) PDK2
SCHEMBL22901507 0.81 FTO (0.33) ABL1
SCHEMBL18180033 0.80 TP53 (0.31)
SCHEMBL22901515 0.78 PDK2 (0.35) PDK2
SCHEMBL22901517 0.78 ALOX15 (0.33) ABL1
SCHEMBL15801313 0.78
SCHEMBL9455626 0.77 CA12 (0.37) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed