SCHEMBL2290182

SCHEMBL2290182

CC(C)(c1ccc(O)cc1)c1ccc(OP(=O)(O)Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.58
ESR2 Q92731 4/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 2/20 0.58
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SRC P12931 1/20 0.46
LTA4H P09960 1/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisphenol A SCHEMBL811003 0.98 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL3693240 0.94 SRC (0.52) ESR1ESR2ALDH1A1CYP3A4KDM4E
SCHEMBL1900143 0.90 ALDH1A1 (0.50) ESR1ESR2ALDH1A1CYP3A4KDM4E
SCHEMBL7193822 0.90 ESR1 (0.50) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL12670502 0.89 ALDH1A1 (0.48) ESR1ESR2ALDH1A1CYP3A4TSHR
Bisphenol A SCHEMBL1610315 0.89 SRC (0.61) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL14023390 0.89 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL811002 0.89 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL6544825 0.89 ALDH1A1 (0.48) ESR1ESR2ALDH1A1CYP3A4KDM4E
Bisphenol A SCHEMBL30608531 0.88 ESR1 (0.51) ESR1ESR2ALDH1A1CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110212179-A1 MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME LIU DAVID 2011-09-01 US claimed
EP-2344578-A2 MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME Liu, David (US) 2011-07-20 EP claimed
WO-2010062678-A2 MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME LIU DAVID (US) 2010-06-03 WO claimed
US-20240209206-A1 Flame Retardant Polycarbonate Composition With High Comparative Tracking Index COVESTRO DEUTSCHLAND AG (DE) 2024-06-27 US disclosed
US-11826951-B2 Temperature-controlled multi-material overprinting CELLINK AB (SE) 2023-11-28 US disclosed
US-20220177497-A1 CONTINUOUS INDUSTRIAL PRODUCTION METHOD OF HIGH-PURITY BISPHENOL A-BIS(DIPHENYL PHOSPHATE) Zhejiang Wansheng Co.,Ltd (CN) 2022-06-09 US disclosed
US-20210069964-A1 TEMPERATURE-CONTROLLED MULTI-MATERIAL OVERPRINTING BICO GROUP AB (SE) 2021-03-11 US disclosed
EP-2010597-B1 POROUS POLYMER BLEND STRUCTURES UNIV QUEENSLAND (AU) 2015-06-17 EP disclosed
WO-2012094708-A1 BONE GRAFT BIOMATERIAL THE UNIVERSITY OF QUEENSLAND (AU) 2012-07-19 WO disclosed
US-8222308-B2 Porous polymer structures THE UNIVERSITY OF QUEENSLAND (AU) 2012-07-17 US disclosed
US-8044108-B2 Porous polymer blend structures THE UNIVERSITY OF QUEENSLAND (AU) 2011-10-25 US disclosed
EP-1173235-A1 POROUS POLYMER SCAFFOLDS FOR TISSUE ENGINEERING Rutgers, The State University (US) 2002-01-23 EP disclosed
US-6337198-B1 A BIODEGRADABLE AND BIOCOMPATIBLE POROUS POLYMER USED IN TISSUE ENGINEERING AND REGENERATION; THE POLYMER HAS A HIGHLY INTERCONNECTED BIMODAL DISTRIBUTION OF OPEN PORE SIZES, HIGH INTERNAL SURFACE AREA, LINEAR ALIGNED PORES ALONG THE WALLS RUTGERS, THE STATE UNIVERSITY 2002-01-08 US disclosed
WO-2000062829-A1 POROUS POLYMER SCAFFOLDS FOR TISSUE ENGINEERING RUTGERS, THE STATE UNIVERSITY (US) 2000-10-26 WO disclosed
US-6103255-A Porous polymer scaffolds for tissue engineering RUTGERS, THE STATE UNIVERSITY (US) 2000-08-15 US disclosed
EP-0990008-A1 SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) IN TOLUENE GUILFORD PHARMACEUTICALS INC. (US) 2000-04-05 EP disclosed
US-6028163-A Solution polymerization of high molecular weight poly(phosphoesters) in toluene GUILFORD PHARMACEUTICALS INC. (US) 2000-02-22 US disclosed
US-5952451-A Solution polymerization of high molecular weight poly(phosphoesters) in toluene GUILFORD PHARMACEUTICALS INC. (US) 1999-09-14 US disclosed
WO-1999000446-A9 SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) IN TOLUENE GUILFORD PHARM INC (US) 1999-05-06 WO disclosed
WO-1999000446-A1 SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) IN TOLUENE GUILFORD PHARMACEUTICALS INC. (US) 1999-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212179-A1 MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME CD68, KIT, ARG2 ESR1 4037/4885ESR2 2359/4885ALDH1A1 2090/4885
US-20220177497-A1 CONTINUOUS INDUSTRIAL PRODUCTION METHOD OF HIGH-PURITY BISPHENOL A-BIS(DIPHENYL PHOSPHATE) ALPP, POF1B, DUSP4 ESR1 97/4885ESR2 262/4885ALDH1A1 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.