Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TYR | P14679 | 3/20 | 0.58 |
| ▸ | ERN1 | O75460 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448262 | 0.88 | TYR (0.53) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL985519 | 0.85 | ERN1 (0.55) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL31063006 | 0.85 | ERN1 (0.55) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL2636573 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL7237898 | 0.82 | ERN1 (0.50) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL24680922 | 0.81 | HDAC4 (0.43) | ALDH1A1TYRERN1TDP1L3MBTL1 | |
| SCHEMBL2467985 | 0.81 | HDAC4 (0.43) | ALDH1A1TYRERN1TSHRL3MBTL1 | |
| SCHEMBL4182784 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TYRERN1TSHRKDM4E | |
| SCHEMBL27590397 | 0.78 | TYR (0.50) | ALDH1A1TYRERN1L3MBTL1PTPN1 | |
| Isopropylbenzene SCHEMBL27542447 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TYRERN1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230074887-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2023-03-09 | — | — | US | disclosed |
| EP-3860984-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-08-11 | — | — | EP | disclosed |
| CN-112912371-A | Flavone derivatives for treating and preventing hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2021-06-04 | — | — | CN | disclosed |
| WO-2020070088-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-04-09 | — | — | WO | disclosed |
| EP-2534281-B1 | METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL | BASF SE (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-8889920-B2 | Process for preparing 4-isopropylcyclohexylmethanol | BASF SE (DE) | 2014-11-18 | — | — | US | disclosed |
| EP-2534281-A2 | METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL | BASF SE (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-20110207968-A1 | PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL | BASF SE (DE) | 2011-08-25 | — | — | US | disclosed |
| WO-2011098432-A2 | METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL | BASF SE (DE) | 2011-08-18 | — | — | WO | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| CN-101054345-B | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2010-06-02 | — | — | CN | disclosed |
| CN-1602291-B | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-101402562-A | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-101054345-A | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-10-17 | — | — | CN | disclosed |
| CN-1602291-A | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-03-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207968-A1 | PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL | CYP2E1, CYP3A4, DHPS | ALDH1A1 147/4885TYR 1154/4885ERN1 3156/4885 |
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | CCNE2, CCNE1, CCNT1 | ALDH1A1 455/4885TYR 2287/4885ERN1 1445/4885 |
| US-20230074887-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | CCNE2, CCNE1, CCNT1 | ALDH1A1 455/4885TYR 2287/4885ERN1 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.