SCHEMBL22902145

SCHEMBL22902145

Cc1ccc(-n2cc(C(C)C)c(C)n2)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
TYMS P04818 1/20 0.38
OPRM1 P35372 1/20 0.37
LMNA P02545 2/20 0.37
TRPA1 O75762 1/20 0.37
CHRM1 P11229 1/20 0.37
SLC6A2 P23975 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 4/20 0.33
PIP4K2A P48426 1/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
DNMT1 P26358 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22902097 0.86 LMNA (0.37) TYMSLMNATRPA1ALDH1A1PKM
SCHEMBL22902088 0.84 TRPA1 (0.35) KDM4ETYMSOPRM1LMNATRPA1
SCHEMBL22902073 0.84 BCHE (0.40) KDM4ETYMSLMNATRPA1CHRM1
SCHEMBL16202089 0.81 KDM4E (0.46) KDM4EOPRM1LMNANPSR1ALDH1A1
SCHEMBL22902074 0.76 CNR1 (0.43) KDM4ELMNANPSR1ALDH1A1MAPT
SCHEMBL22924559 0.74 PTGS1 (0.33) LMNATRPA1CHRM1ALDH1A1PKM
SCHEMBL22902091 0.74 LMNA (0.32) LMNATRPA1
SCHEMBL25762147 0.72 NPBWR1 (0.36) KDM4ELMNANPSR1ALDH1A1MAPT
SCHEMBL22734365 0.69 MAPT (0.48) KDM4ELMNANPSR1ALDH1A1MAPT
SCHEMBL17661892 0.69 LMNA (0.36) KDM4EOPRM1LMNANPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3766879-A1 PESTICIDAL PYRAZOLE DERIVATIVES BASF SE (DE) 2021-01-20 EP disclosed