Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.66 |
| ▸ | RAB9A | P51151 | 13/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558362 | 0.87 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL14546718 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL20558332 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL3894083 | 0.81 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL14985581 | 0.81 | MEN1 (0.67) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL3895629 | 0.81 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL3893324 | 0.81 | GLA (0.54) | NPC1RAB9ATP53NPSR1MEN1 | |
| SCHEMBL3894291 | 0.81 | SIRT2 (0.51) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL22902863 | 0.80 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL3689257 | 0.80 | RAB9A (0.83) | NPC1RAB9ASMN1; SMN2TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | claimed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | claimed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | claimed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | disclosed |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
| WO-2003010143-A1 | DIALKYLHYDROXYBENZOIC ACID DERIVATIVES CONTAINING METAL CHELATING GROUPS AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | NPC1 1408/4885RAB9A 764/4885SMN1; SMN2 1476/4885 |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | NPC1 1513/4885RAB9A 1174/4885SMN1; SMN2 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.