Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904497 | 0.86 | CA1 (0.41) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904571 | 0.84 | DRD2 (0.46) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904360 | 0.84 | DRD2 (0.46) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904569 | 0.84 | DRD2 (0.46) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904494 | 0.83 | PDPK1 (0.42) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904495 | 0.83 | PDPK1 (0.42) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL22904278 | 0.78 | ADORA3 (0.41) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL28875688 | 0.71 | DRD2 (0.40) | IDO1PDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL31627170 | 0.71 | TDP1 (0.52) | DRD2NPSR1 | |
| SCHEMBL27770725 | 0.70 | TDP1 (0.51) | DRD2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |