Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904156 | 0.86 | IDO1 (0.43) | PDPK1CCNB2PRKCBCDK1LYN | |
| SCHEMBL22904277 | 0.84 | DRD2 (0.42) | CA1CA2CA12CA9POLB | |
| SCHEMBL22904407 | 0.84 | DRD2 (0.42) | CA1CA2CA12CA9POLB | |
| SCHEMBL22904279 | 0.84 | DRD2 (0.42) | CA1CA2CA12CA9POLB | |
| SCHEMBL22904278 | 0.81 | ADORA3 (0.41) | CA1CA2CA12CA9PDPK1 | |
| SCHEMBL22904406 | 0.80 | DRD2 (0.43) | CA1CA2CA12CA9DRD2 | |
| SCHEMBL22904494 | 0.79 | PDPK1 (0.42) | PDPK1CCNB2PRKCBCDK1LYN | |
| SCHEMBL22904495 | 0.79 | PDPK1 (0.42) | PDPK1CCNB2PRKCBCDK1LYN | |
| SCHEMBL22904147 | 0.76 | MAOB (0.38) | — | |
| SCHEMBL22102023 | 0.72 | NPSR1 (0.61) | IDO1POLBGAANPSR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |