Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248709 | 0.87 | LOXL2 (0.53) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL9233919 | 0.85 | TSHR (0.62) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL21407732 | 0.84 | TSHR (0.51) | SMN1; SMN2MEN1KMT2ATSHRRAB9A | |
| SCHEMBL2981632 | 0.83 | NR4A1 (0.61) | SMN1; SMN2MEN1KMT2ATSHRHPGD | |
| SCHEMBL6647657 | 0.82 | PKM (0.61) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL29571868 | 0.82 | ALDH1A1 (0.49) | KMT2ATSHRMAPTHPGDLMNA | |
| SCHEMBL22388846 | 0.81 | KMT2A (0.76) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL28488225 | 0.81 | NR4A1 (0.59) | SMN1; SMN2MEN1KMT2ATSHRHPGD | |
| SCHEMBL10485714 | 0.81 | LOXL2 (0.58) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL15628255 | 0.81 | LOXL2 (0.50) | SMN1; SMN2MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528782-B2 | Prodrugs in the modulation of interleukin | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| US-20230167082-A1 | PRODRUGS IN THE MODULATION OF INTERLEUKIN | BRISTOL-MYERS SQUIBB COMPANY | 2023-06-01 | — | — | US | disclosed |
| US-20230167082-A1 | PRODRUGS IN THE MODULATION OF INTERLEUKIN | BRISTOL-MYERS SQUIBB COMPANY | 2023-06-01 | — | — | US | disclosed |
| WO-2021011513-A1 | PRODRUGS IN THE MODULATION OF INTERLEUKIN | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528782-B2 | Prodrugs in the modulation of interleukin | IL2, IL23R, TYK2 | SMN1; SMN2 2768/4885MEN1 4462/4885KMT2A 1701/4885 |
| US-20230167082-A1 | PRODRUGS IN THE MODULATION OF INTERLEUKIN | TYK2, IL2, IRAK2 | SMN1; SMN2 3690/4885MEN1 3999/4885KMT2A 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.